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cathepsine A-gerelateerde arteriopathie met cerebrovasculaire accidenten en leukencefalopathie (aandoening)
cathepsine A-gerelateerde arteriopathie met cerebrovasculaire accidenten en leukencefalopathie
CARASAL
cathepsine A-gerelateerde arteriopathie met CVA's en leuko-encefalopathie
Cathepsin A-related arteriopathy, strokes, leukoencephalopathy
CARASAL - cathepsin A-related arteriopathy, strokes, leukoencephalopathy
A rare genetic cerebral small vessel disease with characteristics of adult-onset primary microangiopathy with severe atherosclerosis of arterioles and secondary leukoencephalopathy. Patients may present with migraine, transient ischemic attacks, stroke with central facial palsy, cognitive dysfunction with impaired concentration, dementia, depression, movement disorder, vertigo, dysphagia, dysarthria, impaired REM sleep, and therapy-resistant hypertension, among others. Brain MRI typically shows a leukoencephalopathy that is disproportionately severe and extensive compared to the clinical disease.
Id1197429000
StatusPrimitive
Associated morphologyatherosclerose
Finding sitestructuur van arteriola
SNOMED CT to Orphanet simple map575553
SNOMED CT to ICD-10 extended map
TargetI67.8
RuleTRUE
AdviceALWAYS I67.8 | POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
CorrelationSNOMED CT source code to target map code correlation not specified