syndroom van keratosis palmoplantaris en oesofageaal carcinoom (aandoening) |
| syndroom van keratosis palmoplantaris en oesofageaal carcinoom |
| Howell-Evans-syndroom syndroom van palmoplantaire hyperkeratose en oesofageaal carcinoom syndroom van palmoplantaire keratodermie en oesofageaal carcinoom
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| Palmoplantar keratoderma esophageal carcinoma syndrome |
| Palmoplantar hyperkeratosis esophageal carcinoma syndrome Howel Evans syndrome Keratosis palmoplantaris esophageal carcinoma syndrome Howel-Evans-Clark syndrome Howel-Evans' syndrome Keratoderma with carcinoma of esophagus Bennion Patterson syndrome Tylosis esophageal carcinoma syndrome
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| A rare genetic disease characterized by thickening of the skin on palms and soles restricted to areas of weight bearing and/or friction (focal, non-epidermolytic palmoplantar keratoderma) and oral and esophageal leukokeratosis, associated with a very high lifetime risk of developing squamous cell carcinoma of the esophagus. The skin lesions appear in childhood and can be complicated by fissuring and infection. |