| MITF-gerelateerd melanoom en niercelcarcinoom-predispositiesyndroom (aandoening) |
| MITF-gerelateerd melanoom en niercelcarcinoom-predispositiesyndroom |
| 'microphthalmia-associated transcription factor'-gerelateerd melanoom en niercelcarcinoom-predispositiesyndroom
'melanogenesis associated transcription factor'-gerelateerd melanoom en niercelcarcinoom-predispositiesyndroom
'melanocyte inducing transcription factor'-gerelateerd melanoom en niercelcarcinoom-predispositiesyndroom
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| MITF-related melanoma and renal cell carcinoma predisposition syndrome |
| Melanogenesis associated transcription factor related melanoma and renal cell carcinoma predisposition syndrome
MITF (melanogenesis associated transcription factor) related melanoma and renal cell carcinoma predisposition syndrome
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| MITF-related melanoma and renal cell carcinoma predisposition syndrome is an inherited cancer-predisposing syndrome due to a gain-of-function germline mutation in the MITF gene, associated with a higher incidence of amelanotic and nodular melanoma, multiple primary melanomas and increase in nevus number and size. It may also predispose to co-occurring melanoma and renal cell carcinoma and to pancreatic cancer. |
