Acute inflammatory disease	Acute nervous system disorder	Chronic brain syndrome	Multiple sclerosis	White matter disease
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Marburg acute multiple sclerosis (disorder)
	Marburg acute multiple sclerosis
	Acute multiple sclerosis Marburg type Acute multiple sclerosis Marburg variant
	Marburg acute multiple sclerosis is a rare variant of multiple sclerosis characterized by a rapidly progressive, aggressive form of multiple sclerosis with numerous large multifocal demyelinating lesions in deep white matter on cerebral MRI that usually leads to severe disability or death within weeks to months without remission. A relapsing form of multiple sclerosis is observed in surviving patients.

Id	766246000
Status	Primitive

Associated morphology	Demyelination
Finding site	Cerebral white matter structure

Clinical course

Sudden onset AND/OR short duration

Associated morphology	Inflammatory morphology
Finding site	Structure of central nervous system
Pathological process	Abnormal immune process

Associated morphology	Demyelination
Finding site	Structure of central nervous system
Pathological process	Abnormal immune process

Clinical course

SNOMED CT to Orphanet simple map

RIVM authorized national diagnosis thesaurus to ICD10 complex mapping reference set

Target	G35
Term	Multipele sclerose

SNOMED CT to ICD-10 extended map

Target	G35
Rule	TRUE
Advice	ALWAYS G35 \| POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
Correlation	SNOMED CT source code to target map code correlation not specified