embryopathie door mycofenolaatmofetil (aandoening)
embryopathie door mycofenolaatmofetil
Mycophenolate mofetil embryopathy
Embryopathy caused by mycophenolate mofetil
A malformative syndrome due to the teratogenic effect of mycophenolate mofetil (MMF), an effective immunosuppressive agent widely used for the prevention of organ rejection after organ transplantation. To date the majority of cases have been offspring of women who received a solid organ transplant. The newborn or fetus generally has external ear anomalies. Cleft lip-palate with micrognathia is frequently observed. Aberrant orofacial cleft has been observed in one case. Ocular anomalies, such as microphthalmia and iris or chorioretinal coloboma are also frequent. Distal limbs anomalies as well as congenital malformations of the heart, kidneys and/or central nervous system may also be observed.
Associated morphologymorfologische afwijking
Causative agentmycofenolaatmofetil
Finding sitestructuur van foetus
Pathological processproces van pathologische ontwikkeling
DHD Diagnosis thesaurus reference set
RIVM authorized national diagnosis thesaurus to ICD10 complex mapping reference set
TermOverige congenitale gestoorde-ontwikkelingssyndromen door bekende exogene oorzaken
SNOMED CT to Orphanet simple map268249
SNOMED CT to ICD-10 extended map
AdviceALWAYS Q86.8
CorrelationSNOMED CT source code to target map code correlation not specified