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hyperinsulinisme door deficiëntie van korte-keten-3-hydroxy-acyl-coenzym-A-dehydrogenase (aandoening)
hyperinsulinisme door deficiëntie van korte-keten-3-hydroxy-acyl-coenzym-A-dehydrogenase
hyperinsulinisme door korte-keten-3-hydroxy-acyl-coenzym-A-dehydrogenasedeficiëntie
hyperinsulinisme door korte-keten-3-hydroxyacyl-CoA-dehydrogenasedeficiëntie
Hyperinsulinism due to short chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency
Hyperinsulinism due to short chain 3-hydroxylacyl-CoA dehydrogenase deficiency
A mitochondrial fatty acid oxidation disorder characterized by hyperinsulinemic hypoglycemia with seizures, and in one case fulminant hepatic failure. Less than 10 cases have been reported to date. The disease can present in infancy or early childhood. It presents with the manifestations of hyperinsulinemic hypoglycemia with vomiting, lethargy and seizures. Complications include coma and sudden death. It has responded well to diazoxide. It is caused by a mutation in the HADH gene (4q22-q26) encoding the SCHAD protein that has a dual function both as an enzyme and an inhibitor of glutamate dehydrogenase. The mode of inheritance is autosomal recessive.
Id721236002
StatusDefined
DHD Diagnosis thesaurus reference set
RIVM authorized national diagnosis thesaurus to ICD10 complex mapping reference set
TargetE71.3
TermStoornissen van vetzuurmetabolisme
SNOMED CT to Orphanet simple map71212
SNOMED CT to ICD-10 extended map
TargetE71.3
RuleTRUE
AdviceALWAYS E71.3 | POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
CorrelationSNOMED CT source code to target map code correlation not specified