| A group of systemic symptoms comprising unexplained fever, drenching night sweats and unexplained, unintentional weight loss, the presence of any one of which is sufficient to constitute B symptoms when the applicable qualifying criteria are met. B symptoms are classically associated with hematological malignancies, particularly lymphoma and leukemia, but may also occur in other cancers. Specific qualifying thresholds and durations are defined by the clinical guideline, staging system or classification being applied. |