Decreased muscle tone	Developmental delay	Disorder of brain	Disorder of skeletal muscle	Genetic disease	Poor muscle tone
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G protein subunit alpha o1-related developmental delay, seizures, movement disorder spectrum (disorder)
	GNAO1-related developmental delay, seizures, movement disorder spectrum
	G protein subunit alpha o1-related developmental delay, seizures, movement disorder spectrum GNAO1-related spectrum
	A rare genetic neurological disorder characterized by a phenotypic spectrum of mild to severe developmental delay and hypotonia, variably associated with intellectual disability, early-onset seizures, and movement disorders, such as dystonia, ataxia, chorea, and dyskinesia. Brain imaging may show delayed myelination, thin corpus callosum, or cerebral atrophy.

Id	1281842000
Status	Primitive

Finding site

Skeletal muscle structure

Has interpretation	Decreased
Interprets	Muscle tone

Finding site	Brain structure
Pathological process	Pathological developmental process

Has interpretation	Abnormally low
Interprets	Muscle tone

SNOMED CT to Orphanet simple map

SNOMED CT to ICD-10 extended map

Target	G93.4
Rule	TRUE
Advice	ALWAYS G93.4 \| POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
Correlation	SNOMED CT source code to target map code correlation not specified