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'cytokine release'-syndroom door immunotherapie met T-cellen met chimerische antigeenreceptor (aandoening)
'cytokine release'-syndroom door immunotherapie met T-cellen met chimerische antigeenreceptor
'cytokine release'-syndroom door immuuntherapie met T-cellen met chimere antigeenreceptor
'cytokine release'-syndroom door CAR-T-celimmunotherapie
Cytokine release syndrome due to chimeric antigen receptor T-cell immunotherapy
CAR T (chimeric antigen receptor T) cell therapy-associated CRS (cytokine release syndrome)
Chimeric antigen receptor-T cell therapy-associated cytokine release syndrome
CAR-T (chimeric antigen receptor T-cell) therapy associated cytokine release syndrome
Chimeric antigen receptor T-cell immunotherapy-associated cytokine release syndrome
A rare systemic condition affecting patients undergoing chimeric antigen receptor (CAR) T-cell therapy and characterized by a systemic inflammatory response due to massive activation of leukocytes with subsequent cytokine release. It can present with a variety of signs and symptoms ranging from mild, flu-like symptoms (such as fever, fatigue, headache, rash, arthralgia, and myalgia) to severe life-threatening manifestations including vascular leakage, disseminated intravascular coagulation, shock and multiple organ failure. Respiratory manifestations are common and range from cough and tachypnea to acute respiratory distress syndrome.
Id1230290005
StatusDefined
Associated morphologyinflammatoire morfologie
Causative agentcytokine
Finding sitestructuur van immuunsysteem
Pathological processafwijkend immuunproces
Clinical courseonverwacht optredend
DHD Diagnosis thesaurus reference set
RIVM authorized national diagnosis thesaurus to ICD10 complex mapping reference set
TargetR65.9
TermSystemisch inflammatoir responssyndroom, niet gespecificeerd
TargetT88.8
TermOverige gespecificeerde complicaties van chirurgische en medische behandeling, niet elders geclassificeerd
TargetY43.3
TermOngewenste gevolgen bij therapeutisch gebruik van overige antineoplastische geneesmiddelen
SNOMED CT to Orphanet simple map542323
SNOMED CT to ICD-10 extended map
TargetD89.8
RuleTRUE
AdviceALWAYS D89.8 | POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
CorrelationSNOMED CT source code to target map code correlation not specified
TargetY84.8
RuleTRUE
AdviceALWAYS Y84.8
CorrelationSNOMED CT source code to target map code correlation not specified