congenitale 'larynx cleft' (aandoening) |
| congenitale 'larynx cleft' |
| aangeboren larynxfissuur congenitale laryngo-tracheo-oesofageale fissuur LTEC aangeboren laryngo-tracheo-oesofageale spleet congenitale laryngoschisis aangeboren laryngo-tracheo-oesofageaal diasteem
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| Congenital laryngotracheoesophageal cleft |
| LTEC - laryngo-tracheo-esophageal cleft
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| A congenital malformation characterized by an abnormal posterior sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus. Five types of laryngo-tracheo-esophageal cleft have been described based on the downward extension of the cleft. The disorder is often associated with other congenital abnormalities. Laryngeal clefts result from failure of fusion of the posterior cricoid lamina and abnormal development of the tracheo-esophageal septum. The disorder appears to be mostly sporadic although some familial cases with suspected autosomal dominant transmission have been reported. |