| At least 30% of the sites on teeth exhibit periodontitis, and interdental attachment loss is at least 5 millimeters with radiographic evidence of bone loss extending to at least the middle third of the root, loss of at least 5 teeth due to periodontitis and no more than 10 opposing pairs of remaining teeth with a need for complex rehabilitation due to masticatory dysfunction, occlusal trauma resulting in tooth mobility, alveolar ridge defects and teeth that have moved from original positions. There is radiographic evidence of clinical attachment or bone loss with a minimum of 2 millimeters over the last 5 years, disease progression exceeds expectations related to biofilm deposits and bacterial control therapies, patient smokes at least 10 cigarettes daily and may be diabetic but exhibits HbA1c levels of at least 7%. |